NOTE: Not advice but it's what I do.
Based on trying to avoid wasting components, multiple range trips and needing to pull bullets.
I tend to lean on the side of not wasting components rather than caution. I also tend to just use Google rather than reloading manuals.
So long as you aren't using a weird powder it's pretty hard to make a truly dangerous load, obviously don't do anything stupid.
I always start with the lowest loads first if the top loads are a little hot.
41-43gr is common in 6.5CM so it's pretty safe to assume the 260 will be safe as in this powder range.
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