Couldn't think of a better place to start than what you are planning.
I have tried every powder and projectile combo I could think of for mine.
My barrel was very picky tho.
129 interlock which I still use a lot for reds and shots inside 300ish
123, and 140 Amax were very accurate.
But I settled on the 130 berger VLD hunting and Win 760 powder. I have good case life, excellent accuracy and and velocity with a low ES.
One powder I haven't tried but have heard is good in the improved is RL16. But I am pretty content with how it goes now.
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