First point is that in general cases for the 6.5 cal are smaller because grain for grain of powder they generate more pressure and more barrel erosion. So powder charge and kinetic energy are less than with the equivalent 7mm. Eg 260 Rem vs 7mm08. Its easier to build an accurate rifle in a lower power cartridge and easier to shoot it well.
The main thing is that for the same bullet weight you get better BC in. 6.5 which improves your probability for shot placement ( but only noticeable at > 300 m and if you use a rangefinder well).
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