and your case SIZE will also make a difference...eg 223 case will matter more if 2 grns different capacity than a 270/36-06 sized case..the percentage of difference will be less
now me personally have never really worried about it..call me lazy but my two main rifles for last 25 years have both been VERY unfussy.... whatever they were fed ,within reason, they both will group them in useful sized group.
the most dramatic test we did was over bench to eliminate human factor and we fired 10 different loads through my .270 every thing from 110grns-160grn projectile size and group was easily covered by playing card 2" wide 3" high...if we had taken out the 2 hottest loads both 130grn...one winchester silver tip the other a norma SP the group was closer to 2".plenty good enough for sub 200yard shoulder shooting.
Bookmarks