Hi, here goes my $.50,
First, what rifle type you are shooting from? I understand that COL is the optimised to your rifle and it is a Bolt action.
If it is a light hunting contour barrel it can be the "over heat" causing it for sure, otherwise a slight variation on the powder weight also can cause POI variants, but not "extreme" like this.
I will follow this thread for more feedback.
Try ask a friend or someone with a good shooting skills to have a go with your rifle or put it on a "fixed" or sturd bench rest style ret to double check.
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