Another approach not mentioned yet is to use Quickload (google it, I'm a slow typist) - this allows the reloader to compare a whole range of powders and select one that looks as if it will give a nice balance of a fullish case, 100% burn (many many loads both good and bad don't have anything like better than 95% burn) and good velocity. It also generates barrel times, which some gifted folk (not me) are able to use to predict likely accurate loads based on barrel harmonics.
Depends on how analytical you like to be. Always verify Quickload data against a manual.
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