That would be if you're a dial twidler would it not? Personally, not being one of the former, I've always sighted in at 200m and never had any problems out to 300m with a 7mm/08 and .308 which is about as far as I'm prepared to shoot, with the odd exception. I'd do the same with a .270 if I owned one.
I suppose it depends on the country you're usually hunting in and what cartridge you're using.
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