I work up loads to find the sweet spot of acceptable velocity combined with a desired level of accuracy. I establish this by shooting a brass / ascending powder charge / bullet combination that initially showed potential. This sometimes fails and I go back to square one. But once a very good load is achieved I often find that with a different powder and bullet accuracy will be best in that same velocity area so long as bullet weight is the same. Other common factors are loads having a full case or nearly full case of powder and velocities being in the upper region of max while not necessarily exceeding the "safe" max load.
The only pressure indicators I have are post shot bolt lift and brass condition. Also, rarely, a blown primer indicating excessive pressure.
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