It's an interesting discussion. Especially around what cartridges have the biggest range of application, something to think about if your budget limits you to one or two rifles. .270 win as you mentioned @mickey Duck can go down to a 100 grain varmint load for wallabies & goats, or up to 150/160 grain high-BC for longer ranges and heavier-bodied game. That's why it was my first rifle, but was replaced with a 7WSM when I was gifted a .243 due to the overlap you mention.
I'd be interested to know what it is about these cartridges that make them more versatile... longer/skinnier cases? Necked down a bit from the original? Certain 'sweet spots' of calibres that seem to work with a wider range of weight?
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