WillB one of my 22-250 rifles has a 22" barrel and I am getting 3607 fps with IMR 8208 XBR with the 55 gr Sierra SBT. This is in Lapua brass and Fed 210M primers. With your 20.5" barrel I would expect you would only lose 60 fps at the most. One of my other 22-250s with a 23.5" barrel is pushing the same projectile at 3661fps with the IMR 8208 XBR and 3611fps with IMR 4895. Same brass and primers.
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