In my experience you'll get slightly lower extreme spreads (for velocity) and maybe better accuracy from 2208. A "goto" load that works very well in a lot of rifles is 46.0 of 2208 for 150 to 165 gn (so will be hot with 168's - work up). I run this with 165 Targex s at 2730 from 22" - 1/3 moa in my LA102.
My 308 hunting load that gives 2550 fps from 21" with 178 Eld-x's is 43.8 of 2208.
2206H will probably give better velocity in shorter barrels . . . .
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