2225 is Hogdon Retumbo and is one of their "Extreme" range of powders. RL25 I understand can be a touch temperature sensitive so the ADI would win that race.
I've used RL22 and it ran well in a 7RemMag but I went 2225 as it appeared to be more available (and it came in a 500g tin rather than the 1lb).
The 2225 meters reasonably well and gives good load density in 7mmRemMag for me.
What's the case you want it for?
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