Answer from me is yes as I have done exactly that many times, always with commercial, large rifleboxer primers, standard and magnum. Always worn safety specs whilst doing but never had one ignite. Also have reprimed cases and shot rounds with these same primers. Worked as expected. Wouldn't have a clue as to whether depriming and repriming affected performance at all but what I tend to do with deprimed primers now is keep them aside for use in fouling and / or non-critical loads.
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