I have a 20" barrel with OB suppressor and went from 165 Gamekings pushed by 2207 to 150 SST pushed by 2206H (faster burn in my shorter barrel). Found i going get improved accuracy from the longer GK pill by having a touch back from the lands but I wasn't happy with the speed (high 2500's) before pressure signs were showing (very tight bolt lift at my most accurate node, still below max load). This prompted me to 2206H and a lighter pill. Marginally less accurate (seated just behind canular) but 2700fps with no pressure signs. I never tried the GK on meat but it was super accurate at the range - less than half MOA. the SST puts holes in deer pretty well so its my hunting round.
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