I've never had much luck with trailboss in small calibre, shotgun powders like blue dot, red dot and 700x or n 320 have always given better groups for me in 303, 3030, 310 cadet, 38 s&W and 38/55.
Old books pretty much all recommend unique, and 6 to10 grains seemed the default setting for rifle 3 to 5 for pistol. No filler needed, I suspect the sharp shove in the back got them to engage better with the rifling. I ran out of unique but have buckets of the others. Blue dot is best for supersonic loads there is a little unburnt powder below 1200fps.
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