The reason that is good advice is wind drift. Unless you go with a big-capacity fast twist .22 chambering, you will be murdered by wind past 300yds. Any 6mm will walk over a std twist .22-250 in wind. I have a heavy 6x47L but am about to take delivery of a lighter walking varminter in 6BR. Super accurate cartridge, far less blast than a .22-250 and WAY less wind drift. Brass lasts forever and cheap to reload.
I have various .223s but if I was starting from scratch now, I'd get a .204 and some sort of 6mm for long range.
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