I'm in a similar situation in some ways - I don't share my office with anyone else at the moment, as long as I'm doing office work rather than going out to do field work (surveyor) I'm isolated whether I work from home or the office.
If I work from home I just have to take a work computer and a bunch of files there to do it, without achieving any more safety or isolation. But I doubt they will put any flexibility into the rules, it will be black and white and they won't want to spend any time deciding whats justified and what isn't.
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