Pretty safe with a 300 win mag? Paired with the right glass, the right shooter, and the right ammo, yes you'd be pretty safe. 300wm is plenty capable of killing deer at those distances.
I wouldn't try and sell you a 243 if you told me you were intent on trying to do so, so no, it doesn't sound like you're being pushed in the wrong direction. I'd pick a 7mm Rem Mag over a 300 if you can get ammo for it though.
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