I have a CZ455. I can tell you that barrel swapping between calibres is not that useful in practice. Everytime you switch between calibres you need to sight in again. If you got your own range in your backyard then it is all good. Otherwise it is a pain to go back to a proper range to do sighting in every time before you use the new calibre.
The appeal of CZ455 is that you can upgrade the barrel yourself. In the USA a lot of people buy Lilja barrels for their CZ455, instant competition class rifle for half the price of Annie. But if you do not intend to do that ever, then there is no point in buy a CZ455 over a 452.
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