100 or so rounds a range trip an a hunting rifle don't go in same sentence you will go away been ripped with your groupings all over the place form heat in the barrel and will teach you nothing, that or you will be there the whole day to do its right and keep it cool.
Get what ever cal takes your fancy been magnum or standard site it in shoot dozen or so then practice while you are there with your 22 you said you have, you will get to know your centre fire better be way cheaper and leave feeling happy with more controlled groups them blasting away
Barrel life is irrelevant you will get over that cal an your first gun and move on to the next before its half rooted
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