Some of the guys on here were recommending a redding body die, a lee collet die for neck sizing and a seating die.
I tried that approach and its worked out great for me, I got my Creedmoor (since sold) going very very nicely using this approach, although I admit I don't ever recall having to actually use the body die. I don't find micro seaters very useful, once I find the sweet spot all a fancy die is good for is sticking out the top of the die box.
I still shoot a 6.5x47 which has small primers, I don't know that I've been able to discern any difference - I'd just go with what you can get in bulk of really top-notch primers. As for projectiles I got on really well with the 130 VLD hunting, I don't recall shooting any big reds with them but certainly several Tahr were no problem.
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