I suppose it is very subjective and depends on the person and the rifle, but I feel like if someone finds a suppressed .270 or 7mm08 comfortable to shoot then a suppressed .308 won't be a problem for them, given the same weight rifle, run-of-the-mill factory ammo etc.
I don't think you can go wrong with a 6.5, I guess 6.5x55 is much easier and cheaper to get factory ammo for, but .260 and 6.5 Creedmoor look pretty good too.
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