If you test it and the bullet gets reliably into the vitals and works, I would say go for it.
Evidence would suggest that it won't. External ballistics are a bit unreliable too.
Evidence does however indicate that small-to-moderate centrefire cartridges with good bullets do work, tremendously well, and a heavier cartridge e.g .300WSM as suggested in the post I replied is absolutely not necessary and counterproductive
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