I am on my second 22-250 (therein lies an issue, the first rifle's barrel was toasted). I dearly love the 22-250, it has the bling factor for sure. I also have a very nice CZ fast twist 223. If I was staring out again it would be the 223 hands down. The 22-250 burns a shit load more powder than the 223 for no substantial gain, burns barrels, mine is limited by a slow twist to lighter projectiles (although this was never an issue for me as mine happily killed many deer, pigs, goats, magpies, minah birds, the odd wild cattle beast), has a very harsh muzzle crack. Also generally the resale on them is poor. Take a look in any gun shop and play spot the 22-250 - if there is one on the shelf there will be several 223s keeping it company.
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