Thread: Sighting in for different grain bullets ?

I am lookin at new glass for my new rifle . A question ? . Can you use a different bullet weight without having to resight yor rifle . What I mean is if I had a dial up turret scope thingie, can you set them to compensate for different weights?. Or am I being stupid? . Is it something you could play with and get a setting that will zero it say at 150 then use the hold over for the different ranges ?