Well, if the can has more gas pressure than the appliance needs the regulator reduces the pressure output to what the appliance requires.
Gas ratio is somewhat critical though - propane burns a lot hotter and is better in colder temperatures as it has a much lower boiling point than butane (-45 rather than butane's 0) which means that as you drop below zero the "standard" iso-butane/propane camping cans aren't much chop. The reason these mixes are what you normally get as the standard is a little bit of safety among other things, as butane is a lot cleaner and less likely to create carbon monoxide if used in an enclosed space.
Some more technical places that sell more hard core gear often have 50/50 ratio cans which burn hotter but if you're planning on cooking in areas where the temp is much below freezing you're better to go with a liquid fuel stove otherwise the contents of your cylinder will separate into liquified butane which won't evaporate and be burned easily and the still-gas-state propane which burns as per normal.
The actual cost of the can may or may not be a factor in efficiency, as different shops often run different prices and it's sometimes luck of the draw in what you get. The mix is critical to performance, 70% butane 30% propane is the usual mix encountered but 50/50 burns hotter.
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