two choices.....dead in the crease if angle is right..or head/neck...if those arent on offer,let it walk..... not a heck of a lot different from using same family of projectiles in any cartridge.
yip you MIGHT get away with shoulder shot 9 times out of 10 , but that 10th one will haunt you.... those pills designed to break up fast so exploding inside chest cavity or partial decapitation are the most reliable killing shots.
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