For shooting past 350M or so you're just about wasting your time with anything less than a zero based on 10 shots - either to prove the rifle will group, or to actually zero from. Having said that heaps of people can still get a deer at 350 ish because "minute of deer" at that range is at least 250x250mm which is about 0.7 5Mil or 2.5 MOA and just about all decent rifles will do that, even 303s.
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