Yes this was my first concern too and I found a few old posts on other forums that had mentioned problems feeding from a CZ 527 too.
So...I loaded 5 dummy rounds to test the .223 mag feeding into the 6x45 Rem barrel and was pleased with the result. See attached vid.
There seems to be .221 Fireball mags available from CZ USA too
https://youtu.be/Qfgst8Tw4Ms
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