Yes you can do it in 243 providing the bolt face has not been modified. With out knowing the mfg of the action you looking at the possibility of locking lug set back if high pressure ammunition is used in any great amount. Even the 1909 Argentine actions as nice as they were only had a 15 Rc hardness thereby limiting their life if put to hard use. The great thing about the 98 Mauser design is all of the safety items incorporated, remember Paul Mauser lost one eye because a rifle of his design blew up in his face. Even as heavy and clunky as the design is they are safe with in reasonable standards of usage.
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