Thread: Suppressors - one size fits many? - is it 'safe'?

I would not say anything grey about it.
The hole size has to be spec'd for the largest Bore/Calibre projectile you will use and the silencer body has to be rated for the largest powder capacity cartridge you will use.

Many manufactures make 2 (or more) spec bodies, 1 for standard size cartridges typically up to 30-06 capacity, then another one for Magnum cartridges.

So if both cartridges have a powder capacity of a 30-06 or less the your only concern is hole size, ie 44 mag and 22-250 could use the same standard body silencer,
but a 6mm Weatherby Magnum and a 308 would need a magnum rated body.
Z