Classic speedy fella that all right but it was designed for 50 to 55 grain projectiles and from what Ive read is pretty much stuck with that size. The 22 250 on the other hand actually started out as a prototype cartridge for the swift project under Wotkyns. Ultimately the design based on the 6mm lee was selected. Wotkyns design was dug up and perfected in the 30s by two wildcatters who called it the 22 varminter and it was a wildcat till picked up by the mainstream makers in the 60s. It nearly matches the swift in speed at the top end but has proved more flexible in reduced loads. Its claimed you can go from 22 rimfire to full noise with good accuracy if you wish.
Both are classic cartridges but having owned a 22 250 before its a return to a happy place.
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