I have built a couple of 338 Feds for customers. I would say they are the best choice for an all round sub and medium range round. Good feeding out of just about any action set up for a 308win, easy for brass and loading, good case design, etc.
As far as ballistics and 'stick busting' ability goes, a long projectile will deflect less than a short fat one. The swedes at Norma figured that out in their tests years ago. I.e. A. 250 or 300gr .338 will be better than a 240gr .45cal .
The bullets out of the states that are dedicated for subsonic hunting loads are the best out there for .30cal or .338cal. Made be 'lee-high', or something like that.
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