For there to be any kind of factual ballistic argument for or against then that callibre needs at least a couple of good game killing projectiles with a BC of .5 or better.
A round set up to shoot to longer ranges that does not have these is absurd.
Burning up your barrel with a round thats badly wind affected makes no sense.
The "flat shooting" thing being a myth because punch it into a ballistics calculator and you will see the projectiles inneficiency is more important than the high muzzle velocity.
If there was a projectile around the 115-120gr mark with a BC of .6 then 25-06 would be shit hot. There is no reason why one could not be made.
What's the point of a hugely over bore short range chambering?
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